Tag Archives | tuberculosis

Introduction of new TB medicines and regimens: An opportunity to strengthen pharmaceutical systems

New medicines and regimens, such as bedaquiline, delamanid, and the newly approved short course regimen, are an exciting development given that first- and second-line TB medicines have limited efficacy and potentially serious adverse effects. With the introduction of new TB medicines and regimens, some countries may target only the minimum WHO-recommended conditions (i.e., proper patient […]

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Improving patient safety and building stronger health systems in Georgia

TB patients on second-line treatment experience a significant number of adverse effects. Some TB medicines result in adverse effects that, if not continuously monitored, can become serious and/or permanent and may hinder patient adherence to treatment. A number of other risk factors can also impact the safety of patients taking TB medicines, including drug interactions […]

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Introducing new TB medicines in five countries

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The Groundbreaker: Rolling Out a New Tuberculosis Drug

Bedaqualine (BDQ) is the first new class of antibiotic to come along in decades. Here’s how it’s being introduced to treat drug-resistant TB in many low- and middle-income countries. Scroll over the photos and click for more information. [huge_it_gallery id=”1″]

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How can private medicine vendors help fight drug-resistant TB?

Tuberculosis is one of the world’s deadliest diseases, and multi-drug resistant TB has contributed significantly to the growing global threat of antimicrobial resistance. Yet in many of the countries most burdened by the disease, about half of those who have TB see private medicine vendors before any other health care professional. That can compound the […]

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Technical Brief: Building Leadership and Governance in Supply Chain Management for the National TB Control Program of the Philippines

The National TB Control Program (NTP) in the Philippines is continuously scaling up its operations in the diagnosis and treatment of TB to achieve the results and deliverables described in the 2010–2016 Philippine Plan of Action to Control Tuberculosis. The USAID-funded SIAPS Program is supporting the NTP in its effort to increase the capacity of various aspects of supply chain management, including leadership and governance. SIAPS supported the NTP in establishing the Drugs and Supplies Management Working Group by developing the terms of reference and facilitating regular meetings with partners and stakeholders.

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Medical Refrigerators Improve Storage Condition at the Peripheral Level and Ensure Quality of Tuberculosis Medicines: Lessons Learned and Opportunities

According to the World Health Organization (WHO), poor-quality medicines and inadequate storage conditions are among the contributing factors that result in poor tuberculosis (TB) treatment outcomes and multidrug-resistant tuberculosis. The recommended temperature to retain the quality of TB medicines is below 25°C, but at the peripheral level in Bangladesh, most TB medicines are stored at the Directly Observed Treatment Short-Course (DOTS) centers of the upazila (subdistrict) health complexes (UHCs) or in the implementing nongovernmental partners’ facilities, where the storage facilities consist of wood or steel lockable cabinets. These cabinets cannot ensure the ideal storage temperature and therefore put expensive and sensitive TB medicines at risk of degradation. In 2012, the US Agency for International Development-funded Systems for Improved Access to Pharmaceuticals and Services (SIAPS) Program, implemented by Management Sciences for Health, conducted a rapid assessment of TB pharmaceutical management in Bangladesh. One recommendation in the assessment report was that options should be considered for lowering the storage temperature at facilities at the upazila level. Both the fifth and sixth Joint Monitoring Missions of the National Tuberculosis Control Program (NTP), conducted in 2010 and 2014, respectively, put forth recommendations to improve storage standards at the upazila level; however, due to a lack of funding, the NTP could not implement these recommendations.

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Guía estandarizada para la integración de los Centros: Especializados de Atención en Salud al SUGEMI

La Reforma del Sector de la Salud en la República Dominicana contempla la organización de un Sistema Único de Gestión del Suministro de Medicamentos e Insumos (SUGEMI) y la prestación de servicios de salud a través de los Servicios Regionales de Salud (SRS).

La etapa inicial de implementación del SUGEMI destacó la gestión del suministro para el primer nivel de atención y de los medicamentos e insumos de los programas de VIH/SIDA y Tuberculosis. Durante esta etapa los Centros Especializados de Atención en Salud (CEAS) participaron en los ejercicios nacionales de programación para la compra, siguiendo la metodología del SUGEMI.

En agosto de 2013, el Departamento de Medicamentos e Insumos (DMI) del Servicio Nacional de Salud (SNS) llevó a cabo un estudio para conocer la situación del suministro en los CEAS. Los resultados de la evaluación del SUGEMI en los CEAS evidenciaron graves deficiencias en la gestión del suministro y en las condiciones y prácticas de almacenamiento. Ante esta situación, el DMI, con apoyo de Systems for Improved Access to Pharmaceuticals and Services (SIAPS), elaboró procedimientos operativos (PO) para la implementación del SUGEMI en los CEAS, e inició la integración de 8 centros en 2015. El plan de trabajo del DMI para 2016, contempla la incorporación escalonada del resto de los CEAS de la red pública al SUGEMI.

Esta guía está dirigida a los Equipos Líderes Regionales e Intrahospitalarios. La guía se organiza alrededor de los pasos secuenciales que facilitan la implementación del SUGEMI en los CEAS. Para cada paso se describen las tareas y se vinculan los instrumentos, formularios y materiales educativos que apoyan la implementación.

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Global Survey of Over 2,000 Users Reveals High Satisfaction with e-TB Manager

By Kelly Sawyer, Technical Associate – TB An 18-point anonymous, global satisfaction survey of over 2,000 users of e-TB Manager from 9 countries yielded a 76% response rate. A web-based tool for managing all the information needed by national tuberculosis (TB) control programs, e-TB Manager integrates data across all aspects of TB control. The user […]

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Bedaquiline Treatment Reaches 200 Patients in Georgia

Georgia is one of the first countries to benefit from the USAID‑Janssen Therapeutics bedaquiline (BDQ) donation program. Along with delamanid, BDQ is one of only two new TB medicines released to the market in over 40 years. These medicines are being used for the treatment of MDR-TB patients, as well as TB patients who have […]

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