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Strengthening TB Pharmaceutical Management in Region IV-A Through Partnership and Capacity Building

In the Philippines, tuberculosis (TB) is the sixth leading cause of death, mostly affecting the poor and vulnerable populations. Stock-outs of TB medicines in public health facilities compromise treatment of patients with TB because of limited access and additional burden of out-of-pocket expenses for medicines. As part of the improvement of the overall supply chain of the TB program, SIAPS has been working with the Department of Health central office with focus on quantification, procurement, storage, distribution, and pharmacovigilance. In addition, the National TB Control Program (NTP) requested SIAPS to develop an action-oriented practical guide for TB pharmaceutical management.

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The Economic Cost of Non-Adherence to TB Medicines Resulting from Stock-Outs and Loss to Follow-Up in the Philippines

A key element of successful tuberculosis (TB) control programs is adherence to treatment. Non-adherence results in increased length and severity of illness, death, disease transmission, and drug resistance. The purpose of this study was to estimate the morbidity and mortality impact and economic costs of non-adherence to TB medicines resulting from treatment interruption due to stock-outs or loss to follow-up (LTFU).

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Practical Guide for the Quantification of Anti-TB Medicines: Guidelines for Quantification and Supply Planning for Procurement

This guide is intended to serve as a reference for national-level quanitification, forecasting, and supply planning to inform the procurement of anti-TB medicines in the Philippines. It provides practical guidance for program managers, technical staff, and other key personnel, outlining common considerations and best practices for quantification, and highlighting different methods. It also includes specific guidance for the collection, review, and analysis of data, as well as for building forecast assumptions. To aid in completing quantification exercises, this guide also includes instructions for using QuanTB—an electronic quantification and early warning system designed by SIAPS to improve procurement processes, ordering, and supply planning for TB treatment.

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Improving data for decision making: Philippines adopts SIAPS-developed Pharmacovigilance Monitoring System

With the introduction of new anti-tuberculosis (TB) medicines and novel TB treatment regimens in the Philippines, active pharmacovigilance is needed to ensure that both patient safety and the effectiveness of the treatment are monitored. As an important step in pharmacovigilance implementation, the Philippine Department of Health – Pharmaceutical Division (DOH-PD) has adopted the Pharmacovigilance Monitoring […]

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Ensuring Sustainable Access to TB Medicines through Inclusion in the Philippine National Formulary

To begin the project, SIAPS helped coordinate regular planning meetings and discussions with the NTP’s Drugs and Supplies Management (DSM) sub-technical working group. SIAPS then facilitated collaboration among the NTP, the PD, WHO, and the GDF.

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Pharmacovigilance Monitoring System Readiness Assessment, Philippine Department of Health

SIAPS, in partnership with the FDA, NTP, and LCP-NCPR, conducted a readiness assessment to determine the current information technology (IT) infrastructure, human resources, processes, and data management and quality control mechanisms available and to identify gaps in the current PV recording and reporting of patients in the seven Programmatic Management of Drug-Resistant TB (PMDT) treatment facilities implementing the 9MTR for multidrug-resistant (MDR)-TB study. The results of this assessment will provide inputs for developing the PViMS implementation plan.

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Situation Analysis: Regulatory Data Management System of Philippines FDA

The goals of this situation analysis were to evaluate the current status of the PFDA’s overall regulatory information management system, with a focus on medicine registration data management, and to develop recommendations and an action plan to cultivate a more robust regulatory information management system, including the required IT solutions to manage licensing of drug establishments and the registration of pharmaceutical products, as well as other operations of the PFDA.

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Technical Brief: Building Leadership and Governance in Supply Chain Management for the National TB Control Program of the Philippines

The National TB Control Program (NTP) in the Philippines is continuously scaling up its operations in the diagnosis and treatment of TB to achieve the results and deliverables described in the 2010–2016 Philippine Plan of Action to Control Tuberculosis. The USAID-funded SIAPS Program is supporting the NTP in its effort to increase the capacity of various aspects of supply chain management, including leadership and governance. SIAPS supported the NTP in establishing the Drugs and Supplies Management Working Group by developing the terms of reference and facilitating regular meetings with partners and stakeholders.

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The tuberculosis profile of the Philippines, 2003–2011: advancing DOTS and beyond

Vianzon R, Celina Garfin AM, Lagos A, Belen R. The tuberculosis profile of the Philippines, 2003-2011: Advancing DOTS and beyond. Surveillance Report. 2013.

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Economic Cost of Non-Adherence to TB Medicines Resulting from Stock-Outs and Loss to Follow-Up in the Philippines

One of the key elements of successful tuberculosis (TB) control programs is adherence to treatment, and this is a cornerstone of most international and national policies and guidelines. Non-adherence is often due to patient-related factors, but can also be a result of provider issues, such as stock-outs of TB medicines. Non-adherence results in increases in length and severity of illness, deaths, disease transmission, and drug resistance. These have economic consequences in terms of costs and loss of income for patients and their families and also costs to the health system.

 

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