Archive Antimicrobial Resistance

Inventory of Key USAID and Global AMR-related System Strengthening Resources/Interventions

This inventory is a selected list of resources and interventions that support antimicrobial resistance (AMR) containment. The objective of this inventory is to provide a list of key resources, tools, and interventions that create or strengthen systems that are necessary to improve antimicrobial use and AMR containment. Along with the full references, links are provided directly … Read more

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Supporting drug and therapeutics committees in Sierra Leone to promote safe, appropriate medicine use

Irrational medicine use and poor pharmaceutical management at all levels are widespread problems in many developing countries, including Sierra Leone. Misuse, underuse, and overuse of medicines; weak systems that compromise medicine safety; the waste of scarce resources due to expiry; and the rise of antimicrobial resistance (AMR) are particularly worrying because they directly affect health … Read more

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In the news: Capacity building to defeat AMR

Antimicrobial resistance (AMR) is one of the world’s most pressing global health threats and could erode the progress made in the treatment of HIV/AIDS, tuberculosis, malaria, and many other infectious diseases. Although AMR occurs naturally, many interrelated factors, including excessive or inappropriate use of antibiotics, poor control practices, and infection prevention, contribute to its acceleration … Read more

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Combating Antimicrobial Resistance with Strong Coalitions

Antimicrobial resistance (AMR) occurs when microorganisms develop a resistance to a medicine that was originally intended to disable or kill them. While microbes naturally develop resistance to antimicrobials over time, AMR is accelerated by the overuse and misuse of antimicrobial medicines and non-adherence to treatment regimens. AMR jeopardizes the effectiveness of complex surgeries and procedures … Read more

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Building Coalitions for Containing Antimicrobial Resistance: A Guide

This guide aims to help individuals, organizations, and governments develop, establish, and maintain effective multidisciplinary and multisectoral coalitions to combat AMR. This document provides guidance on building and strengthening coalitions to combat AMR through five key elements. It primarily focuses on the creation and establishment of new coalitions; however, these elements are relevant throughout the … Read more

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Using Electronic Pharmacy Dispensing Data for Surveillance of Outpatient Antibiotic Consumption and Monitoring of Antibiotic Prescribing Practices at District and Provincial Hospitals in the South African Public Sector

The primary aim of this study was to assess the feasibility of using electronic pharmacy dispensing data extracted from RxSolution® for the surveillance of outpatient (ambulatory) antibiotic consumption and monitor antibiotic prescribing practices at district and provincial hospitals in public health facilities in North West Province, South Africa, between April 2013 and March 2015. This … Read more

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Technical Program Update: Combating Antimicrobial Resistance with Stronger Health Systems

Antimicrobial resistance (AMR) is one of the world’s most pressing and urgent global health threats— one that could erode the current progress against tuberculosis (TB), malaria, HIV/AIDS, and many other infectious diseases. AMR poses an enormous threat to the safety and feasibility of complex surgeries and procedures like organ transplantation and chemotherapy, but could also … Read more

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Every Breath Counts: Strengthening Pharmaceutical Systems for Better Health Outcomes with Pneumonia

By Jane Briggs, Principal Technical Advisor More than 900,000 children die of pneumonia each year (more than malaria, measles, and HIV/AIDS combined), according to the World Health Organization. Many of these cases go undiagnosed and untreated. How can this be when we know what works? A five-day, twice-daily amoxicillin regimen—in either dispersible tablet (DT) or oral … Read more

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Systems-based Approaches to Improving Medication Adherence

With the shift from a disease landscape that focuses on the treatment of acute and short-term illnesses to one that faces an increasing burden of chronic diseases that may require life-long medicine use, the role of medicines in ensuring a healthy population is more important than ever. However,even when medicines are available, patients may not … Read more

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