New medicines and regimens, such as bedaquiline, delamanid, and the newly approved short course regimen, are an exciting development given that first- and second-line TB medicines have limited efficacy and potentially serious adverse effects. With the introduction of new TB medicines and regimens, some countries may target only the minimum WHO-recommended conditions (i.e., proper patient […]
Vianzon R, Celina Garfin AM, Lagos A, Belen R. The tuberculosis profile of the Philippines, 2003-2011: Advancing DOTS and beyond. Surveillance Report. 2013.
Comprehensive strategies and actions for monitoring the safety of medicines are essential to a well-functioning pharmaceutical sector. The links below highlight recent SIAPS Program work in priority and emerging health issues to strengthen health systems. SIAPS Voices series “You can’t achieve UHC without thinking about gender” In public health, when you’re designing an intervention you’re […]
To learn more about SIAPS program activities worldwide, please read our annual report for program year 5.
Namibia faces a dual public health burden of HIV and AIDS and tuberculosis (TB). Critical to the treatment and management of these diseases is an effective workforce that can provide quality pharmaceutical services throughout the country. Pharmacists and pharmacist assistants (PAs) play critical roles in dispensing life-saving medications, monitoring patient health and progress, and educating both patients and other health professionals about proper medication use, storage, and dispensing practices. To meet the high demand for quality pharmaceutical services and to ensure that pharmacy personnel needs are being met, the US Agency for International Development (USAID)-funded Systems for Improved Access to Pharmaceuticals and Services (SIAPS) Program supported the Government of the Republic of Namibia in the long-term planning of pharmaceutical human resources and building the capacity of two local institutions to provide pre-service and in-service pharmaceutical management training.
Economic Cost of Non-Adherence to TB Medicines Resulting from Stock-Outs and Loss to Follow-Up in the Philippines
One of the key elements of successful tuberculosis (TB) control programs is adherence to treatment, and this is a cornerstone of most international and national policies and guidelines. Non-adherence is often due to patient-related factors, but can also be a result of provider issues, such as stock-outs of TB medicines. Non-adherence results in increases in length and severity of illness, deaths, disease transmission, and drug resistance. These have economic consequences in terms of costs and loss of income for patients and their families and also costs to the health system.
Medical Refrigerators Improve Storage Condition at the Peripheral Level and Ensure Quality of Tuberculosis Medicines: Lessons Learned and Opportunities
According to the World Health Organization (WHO), poor-quality medicines and inadequate storage conditions are among the contributing factors that result in poor tuberculosis (TB) treatment outcomes and multidrug-resistant tuberculosis. The recommended temperature to retain the quality of TB medicines is below 25°C, but at the peripheral level in Bangladesh, most TB medicines are stored at the Directly Observed Treatment Short-Course (DOTS) centers of the upazila (subdistrict) health complexes (UHCs) or in the implementing nongovernmental partners’ facilities, where the storage facilities consist of wood or steel lockable cabinets. These cabinets cannot ensure the ideal storage temperature and therefore put expensive and sensitive TB medicines at risk of degradation. In 2012, the US Agency for International Development-funded Systems for Improved Access to Pharmaceuticals and Services (SIAPS) Program, implemented by Management Sciences for Health, conducted a rapid assessment of TB pharmaceutical management in Bangladesh. One recommendation in the assessment report was that options should be considered for lowering the storage temperature at facilities at the upazila level. Both the fifth and sixth Joint Monitoring Missions of the National Tuberculosis Control Program (NTP), conducted in 2010 and 2014, respectively, put forth recommendations to improve storage standards at the upazila level; however, due to a lack of funding, the NTP could not implement these recommendations.
Georgia is one of the first countries to benefit from the USAID‑Janssen Therapeutics bedaquiline (BDQ) donation program. Along with delamanid, BDQ is one of only two new TB medicines released to the market in over 40 years. These medicines are being used for the treatment of MDR-TB patients, as well as TB patients who have […]
In 2012, bedaquiline was conditionally approved by the U.S. Food and Drug Administration for the treatment of drug-resistant tuberculosis (TB), making it the first new TB drug to enter the market in more than 40 years. With the rise of multidrug-resistant and extensively drug-resistant TB leaving patients with fewer treatment options, the approval of bedaquiline […]
In April 2015, USAID and Janssen Therapeutics officially launched the bedaquiline (BDQ) donation initiative, under which Janssen committed to providing free BDQ to 30,000 patients with multidrug-resistant tuberculosis (MDR-TB) over a four-year period. Along with delamanid, BDQ is one of only two new TB medicines released to the market in over 40 years. These medicines […]
- Rapport de quantification des produits de la santé reproductive, maternelle, néonatale et infantile pour la période de janvier 2017 à décembre 2020
La présente activité avait pour objectif d’apporter un soutien au Ministère de la Santé et de l’Hygiène publique (MSHP) pour […]
Project dates: September 2012 – December 2016
The Department of Health-Pharmaceutical Division (DOH-PD) and National TB Program (NTP) in the Philippines adopted the web‐based application Pharmacovigilance Monitoring […]