A strong pharmaceutical management system is critical for responding to and preventing public health emergencies. The US Agency for International Development (USAID)-funded Systems for Improved Access to Pharmaceuticals and Services (SIAPS) Program, implemented by Management Sciences for Health (MSH), is helping four countries affected by Ebola—Sierra Leone, Guinea, Mali, and Benin—recover and rebuild essential drug management and delivery services and to increase their capacity and sustainability. The two-year project began in 2015.