According to the World Health Organization, many countries spend 30–40% of their health care budgets on medicines and medical commodities, and a significant amount of the funds are wasted because of irrational medicines use and inefficiencies in stock management due to lack of skills. Other serious problems that health care organizations face include the overuse of antimicrobials, which increases the risks of antimicrobial resistance, leads to increased adverse drug reactions (ADRs), and results in considerably higher costs associated with drug use. Training pharmacy personnel on proper handling of medicines can help improve the proper handling and dispensing of medicines, rational use of medicines, and adherence to treatment to improve patient health outcomes. The primary objective of the HIV/TB pharmaceutical management and supply chain training was to develop the skills of the pharmacy personnel on proper management of HIV and TB medicines in health facilities.