SIAPS worked with global and in-country partners to improve access to and use of life-saving medicines for women and children, thereby contributing to ending preventable child and maternal deaths. By promoting a pharmaceutical systems strengthening approach, SIAPS activities went beyond addressing supply chain challenges to incorporate interventions to positively affect the system as a whole, from strengthening pharmaceutical legislation, regulations, and policies to supporting appropriate community case management (CCM) and patient-centered care. SIAPS strategies that were implemented at the global and country levels included improving governance of pharmaceutical systems, strengthening supply chain management (SCM) capacity, increasing the availability of pharmaceutical information for decision making, developing appropriate pharmaceutical financing strategies, and promoting rational use of medicines and supplies.