Tag Archives | Drug Utilization Review

Encouraging increased adherence to treatment standards through drug utilization reviews in Ukraine

When doctors and patients fail to adhere to proper standards of treatment, it results in a higher disease burden, including greater financial costs, mortality, and morbidity. In Ukraine, the need to encourage better adherence to standard treatment guidelines became clear in 2011, when a study by SIAPS Program’s  predecessor, the Strengthening Pharmaceutical Systems (SPS) Program, […]

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Drug Use Reviews—A Practical Strategy to Ensure the Rational Use of Anti-Tuberculosis Medicines

This manual is intended as to aid national tuberculosis program (NTP) managers, national pharmacovigilance center managers (NPV), tuberculosis (TB) service delivery providers, health care providers (physicians, pharmacists, nurses, public health officers and other health care professionals), academic institute staff, nongovernmental organizations, researchers, and any other staff working in organizations or individuals who are interested or involved in monitoring and improving medicine use to provide high quality treatment for susceptible tuberculosis (DS-TB) and particularly for drug-resistant tuberculosis (DR-TB).

The manual lists and describes the various steps involved to conduct a DUR. It also provides detailed drug information on World Health Organization’s (WHO) recommended medicines for the treatment of DS-TB and DR-TB. Additionally, the manual provides criteria for reviewing medicines used for TB treatment and also some suggested performance benchmarks or targets for illustrative purposes. Generic data collection forms are also included for local adaptation and use.

Most of the recommendations provided in this manual are generic, describe general principles, and provide a comprehensive, step-by-step explanation of:

  1. Developing context specific DUR criteria according to best available evidence
  2. Collecting and analyzing existing available data
  3. Providing feedback and taking action based on DUR findings when indicated
  4. Reviewing the DUR strategy to identify opportunities for program improvement to provide high quality treatment

These guidelines are intended to be modified according to national or regional specific regulations and treatment practices so they can be used by national TB control programs and their administrative divisions.

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Decreasing the Burden of TB Through Collaboration and Streamlined Approaches

The state of tuberculosis (TB) is in a tug-of-war as current challenges threaten to undo past successes. One of the primary hurdles currently facing TB prevention and cure is the emergence of strains that are resistant to at least two of the most effective medicines (rifampicin and isoniazid). So-called drug-resistant (DR)-TB arises when patients are […]

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