Tag Archives | Antimicrobial Resistance

Inventory of Key USAID and Global AMR-related System Strengthening Resources/Interventions

This inventory is a selected list of resources and interventions that support antimicrobial resistance (AMR) containment. The objective of this inventory is to provide a list of key resources, tools, and interventions that create or strengthen systems that are necessary to improve antimicrobial use and AMR containment. Along with the full references, links are provided directly to the documents or to sites from where the documents can be downloaded. The intention is to periodically update the inventory as new resources, tools, and evidence-based interventions become available.

Read full story · Comments are closed

Supporting drug and therapeutics committees in Sierra Leone to promote safe, appropriate medicine use

Irrational medicine use and poor pharmaceutical management at all levels are widespread problems in many developing countries, including Sierra Leone. Misuse, underuse, and overuse of medicines; weak systems that compromise medicine safety; the waste of scarce resources due to expiry; and the rise of antimicrobial resistance (AMR) are particularly worrying because they directly affect health outcomes. Because of a lack of sound data for decision making, health workers may need to select products for medicines lists, supply, and prescribing based on observation and preferences. SIAPS is facilitating the selection of appropriate, safe products to be procured and used at different levels of the public health system. Promoting rational medicine use cuts down on waste, improves health outcomes, and helps prevent the spread of AMR.

Read full story · Comments are closed

In the news: Capacity building to defeat AMR

Antimicrobial resistance (AMR) is one of the world’s most pressing global health threats and could erode the progress made in the treatment of HIV/AIDS, tuberculosis, malaria, and many other infectious diseases. Although AMR occurs naturally, many interrelated factors, including excessive or inappropriate use of antibiotics, poor control practices, and infection prevention, contribute to its acceleration […]

Read full story · Comments { 0 }

Combating Antimicrobial Resistance with Strong Coalitions

Antimicrobial resistance (AMR) occurs when microorganisms develop a resistance to a medicine that was originally intended to disable or kill them. While microbes naturally develop resistance to antimicrobials over time, AMR is accelerated by the overuse and misuse of antimicrobial medicines and non-adherence to treatment regimens. AMR jeopardizes the effectiveness of complex surgeries and procedures […]

Read full story · Comments { 0 }

Building Coalitions for Containing Antimicrobial Resistance: A Guide

This guide aims to help individuals, organizations, and governments develop, establish, and maintain effective multidisciplinary and multisectoral coalitions to combat AMR. This document provides guidance on building and strengthening coalitions to combat AMR through five key elements. It primarily focuses on the creation and establishment of new coalitions; however, these elements are relevant throughout the lifespan of a coalition, and revisiting each periodically may be important as coalitions grow and evolve, expand in scope or wane and need to be revitalized. In addition, the elements of coalition building may not necessarily occur in strict sequential order. Depending on the context and existing systems in place, coalitions may be able to use situational analyses that have already been conducted or utilize an existing active network. In each setting, it is important to understand the needs of the coalition and focus on the elements of this guide that align best with those needs.

Read full story · Comments are closed

How can private medicine vendors help fight drug-resistant TB?

Tuberculosis is one of the world’s deadliest diseases, and multi-drug resistant TB has contributed significantly to the growing global threat of antimicrobial resistance. Yet in many of the countries most burdened by the disease, about half of those who have TB see private medicine vendors before any other health care professional. That can compound the […]

Read full story · Comments { 0 }

Using Electronic Pharmacy Dispensing Data for Surveillance of Outpatient Antibiotic Consumption and Monitoring of Antibiotic Prescribing Practices at District and Provincial Hospitals in the South African Public Sector

The primary aim of this study was to assess the feasibility of using electronic pharmacy dispensing data extracted from RxSolution® for the surveillance of outpatient (ambulatory) antibiotic consumption and monitor antibiotic prescribing practices at district and provincial hospitals in public health facilities in North West Province, South Africa, between April 2013 and March 2015. This was an exploratory project to develop hypotheses on the volume of antibiotics used and prescribing patterns.

Read full story · Comments are closed

Technical Program Update: Combating Antimicrobial Resistance with Stronger Health Systems

Antimicrobial resistance (AMR) is one of the world’s most pressing and urgent global health threats— one that could erode the current progress against tuberculosis (TB), malaria, HIV/AIDS, and many other infectious diseases. In conjunction with World Antibiotic Awareness Week (14-20 November), the SIAPS Program has published a technical program update on Combating Antimicrobial Resistance with Stronger Health […]

Read full story · Comments { 0 }

Technical Program Update: Combating Antimicrobial Resistance with Stronger Health Systems

Antimicrobial resistance (AMR) is one of the world’s most pressing and urgent global health threats— one that could erode the current progress against tuberculosis (TB), malaria, HIV/AIDS, and many other infectious diseases. AMR poses an enormous threat to the safety and feasibility of complex surgeries and procedures like organ transplantation and chemotherapy, but could also make childbirth, minor infections, and hospital stays more perilous. While AMR has emerged as a critical issue at the global level, current efforts to address AMR are insufficient to curb its spread. Immediate, cross-cutting, and multidisciplinary action is required to adequately address the multidimensional drivers of AMR. In the health sector, strengthening the systems through which health services and medicines are provided is a prerequisite to making progress against AMR.

This technical program update discusses how the Systems for Improved Access to Pharmaceuticals and Services (SIAPS) Program, funded by the US Agency for International Development (USAID), is working to address AMR through a health system strengthening approach with interventions spanning the global, regional, national, and local levels.

Read full story · Comments are closed

Systems-based Approaches to Improving Medication Adherence

With the shift from a disease landscape that focuses on the treatment of acute and short-term illnesses to one that faces an increasing burden of chronic diseases that may require life-long medicine use, the role of medicines in ensuring a healthy population is more important than ever.

However,even when medicines are available, patients may not take them as directed. In other words, they may not adhere to the treatment prescribed to them. This problem is surprisingly widespread. Several studies have estimated that in developed countries, only approximately 50% of patients who suffer from chronic diseases take their medicines as directed.

This document suggests a health systems strengthening (HSS) approach to addressing
medication adherence issues, with a particular emphasis on its application in low- and middle-income settings. Chapter 2 reviews the importance of considering health systems in improving medication adherence and introduces a system-based framework, while Chapters 3–5 discuss approaches, interventions, and activities that span the health system as described at the
macro, meso, and micro levels and provide implementation examples.

Read full story · Comments are closed